Are you at risk of pulmonary embolism?

Are you at risk of pulmonary embolism?

Think of it as prevention.

The point of DNA testing is that you can actually do something about your condition. This is especially true for DNA test for venous thromboembolism. From all the tests you can have done in Futura Genetics, this one can literally save your life. Want to know why?

Venous thromboembolism develops when the fragile balance between blood coagulation and dissolution of the thrombus is impaired. Normally, once the injury is fixed, thrombus is dissolved. More than 20 different molecules participate in coagulation and fibrinolysis. The cascade itself is quite complicated and delicate process. There are plenty of chances for things to go wrong.

Did you know? Our body is constantly prepared to fix any injuries. You don’t necessarily have to cut your finger or graze a knee, tiny molecules circulating in your blood are ready to gather and create protective cluster even when nothing bleeds externally. Thrombus creation naturally occurs inside the veins at the “intersections.” When the vein is dividing or bending, there is an extra pressure on its wall. It possesses certain risks of rupture. That is why those tine molecules responsible for creating thrombus occur on greater extent right there.

Thrombosis happens when a thrombus or its part breaks off and travels via the blood stream until it gets stuck. It can cause severe circulatory disorder. Depending on where a thrombus blocks the vein you can suffer from vein thrombosis, heart attack, stroke or pulmonary embolism. The condition of being predisposed to thrombus creation is called thrombophilia. It can be both inherited as well as acquired from bad health habits and external factors.

Inherited predisposition to thrombophilia means that there is a mutation or mutations in genes regulating blood coagulation and fibrinolysis:

Mutation in gene for Factor V, so called Leiden mutation. The most dangerous one.
Mutation in gene for prothrombin which is Factor II.
Mutation in gene MTHFR. This one is considered to be dangerous during pregnancy.
The severity depends on whether the mutation affects only 1 copy of the gene or both. Logically, mutations in both copies means greater risk of thrombosis.

Other risk factors that you can more or less influence and change:

  • Smoking
  • Obesity
  • Varicose veins
  • Immovability or low physical activity (leg in gypsum, long term sitting)
  • Hormonal contraception. Together with Leiden mutation it increases the risk of thrombosis 30 times.
  • Hormonal substitutional therapy during menopause
  • Pregnancy and/or childbed
  • Cancer
  • Chronic intestinal diseases
  • Sepsis
  • Autoimmune diseases (i.e. diabetes)

Do you smoke more than 20 cigarettes a day?

Then you should read this. Overweight smokers are at really high risk of thrombosis. And that is something that they can actually change. At least a little bit. Many obese patients who are trying to handle their weight are being encouraged to undergo DNA tests for thrombophilia. But with a normal person, it is not that easy. If one is worried about his chances to develop thrombosis, he must rely on a general practitioner and his opinion. If he decides a person doesn’t belong to risk group, he won’t send him to a specialist. Even if the practitioner decides to send his patient to the specialist, it can take ages, because specialists are very busy and their waiting list is usually really long. That can be fatal for a person with a risk mutation.

Luckily for you, with Futura Genetics, you can learn the results much faster! And it gets ever better. We don’t need your blood! All you have to do is to order the test for venous thromboembolism, spit into a tube and after 3 weeks, you simply know! We want to give people a possibility of a fast way how to avoid possible severe health complications.

Don’t take your chances.

Risk mutations occur within European population with a striking frequency. 1 out of 1000 develops vein thrombosis. It kills even more patients than AIDS, breast cancer, prostate cancer and traffic accidents together.

Futura Genetics provides 27 more DNA tests for inherited disease. If you are planning to have a baby or you have a family history of inherited disease or you just simply want to know whether you carry a mutation that can cause a serious disease or not, just take the test.

“An ounce of prevention is worth more than a million pounds of cure.”

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